Research

SARS-coronavirus RNA synthesis: understanding the core of a sophisticated complex

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Title	SARS-coronavirus RNA synthesis: understanding the core of a sophisticated complex
Period	10 / 2007 - 09 / 2011
Status	Current
Dissertation	Yes
Data Supplier:	NWO

Abstract

The highly conserved polymerase and helicase enzymes are prime targets for antiviral therapy. Through combining biochemical, structural and virological studies, I aim to characterize these enzymes and contribute to rational drug design.

Abstract (NL)

De sterk geconserveerde polymerase en helicase enzymen zijn primaire doelen voor antivirale therapie. Door het combineren van biochemische, structurele en virologische studies, is mijn doel deze enzymen te karakteriseren en bij te dragen aan medicijnontwerp.

Related organisations

Secretariat	Leiden University Medical Center - LUMC (UL)
Financier	Netherlands Organization for Scientific Research (NWO)

Related people

Supervisor	Prof.dr. E.J. Snijder
Doctoral/PhD student	Ing. A.J.W. te Velthuis

Classification

D21300	Biochemistry
D22100	Microbiology

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