| Title | Psoriasis is associated with increased beta-defensin genomic copy number. |
|---|---|
| Published in | Nature Genetics, Vol. vol. 40, p.p. 23-p. 25. |
| Author | Hollox, E.J.; Huffmeier, U.; Zeeuwen, P.L.J.M.; Palla, R.; Lascorz, J.; Rodijk-Olthuis, D.; Kerkhof, P.C.M. van de; Traupe, H.; Jongh, G. de; Heijer, M. den; Reis, A.; Armour, J.A.; Schalkwijk, J. |
| Date | 2008 |
| Type | article |
| Summary | Psoriasis is a common inflammatory skin disease with a strong genetic component. We analyzed the genomic copy number polymorphism of the beta-defensin region on human chromosome 8 in 179 Dutch individuals with psoriasis and 272 controls and in 319 German individuals with psoriasis and 305 controls. Comparisons in both cohorts showed a significant association between higher genomic copy number for beta-defensin genes and risk of psoriasis. |
| Publication | http://repository.ubn.ru.nl/handle/2066/71309 |
| OpenURL | Search this publication in (your) library |
| Persistent Identifier | urn:nbn:nl:ui:22-2066/71309 |
| Metadata | XML |
| Repository | Radboud University Nijmegen |
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