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Person

Prof.dr. P. ten Dijke

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Expertise	Signal transduction; Regulation of gene expression; Polypeptide growth factors in angiogenesis, fibrosis and cancer; cDNA micro-arrays; Proteomics; Functional genomics; TGF-beta; BMP; Activin; Smad; Serine/threonine kinase receptors
Expertise (NL)	Signaal transductie; Regulatie van gen expressie; Polypeptide groeifactoren in angiogenese, fibrose en kanker; cDNA micro-arrays; Proteomics; Functional genomics; TGF-beta; BMP; Activine; Serine/threonine kinase receptoren, Smad
Grants/prizes	NWO-Vici 2005

Active as

Professor
Organisation	Department of Molecular Cell Biology (UL)
Chair (EN)	Molecul Cell Biology, and with speciality Signal Transduction
Chair (NL)	Moleculaire celbiologie, en in het bvijzonder signaaltransductie
Phone	+31-71-5269271
Email	p. ten_dijke -at- lumc. nl
URL	http://www.lumc.nl/con/1050/40835/901291135432537

Current research

(the most recent research is at the top)
Project leader	Targeting BMP and LRP5 signaling to control bone formation
Project leader	Biosynthesis and function of base J, a new base in the nuclear DNA of kinetoplastid parasites
Project leader	The role of TGF[beta] and notch signaling in the development of radiation-induced telangiectasia

Completed research projects

(the most recent research is at the top)
Project leader	Subversion of TGF-beta/Smad signaling in cancer: analysis of TGF-beta receptor-initiated intracellular responses distinct from Smad activation
Project leader	Identification and functional characterization of intracellular signaling proteins controlling transforming growth factor-beta-induced growth arrest

Classification

D23120	Oncology
D21400	Genetics

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